Risk factors for underuse of lung-protective ventilation in acute lung injury
نویسندگان
چکیده
منابع مشابه
Predictors of mortality in acute lung injury during the era of lung protective ventilation.
BACKGROUND Lung protective ventilation has been widely adopted for the management of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Consequently, ventilator associated lung injury and mortality have decreased. It is not known if this ventilation strategy changes the prognostic value of previously identified demographic and pulmonary predictors of mortality, such as resp...
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Objective(s): To investigate the protective effect of S-nitrosoglutathione (SNG) pretreatment on acute lung injury (ALI) in septic rats. Materials and Methods: We constructed a rat model of sepsis by cecal ligation and perforation (CLP), and randomly divided into Sham, CLP, and CLP+SNG (0.25 and 0.5 mg/kg) groups. We used H&E; staining an...
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B oth observational and epidemiologic studies have identified clinical variables associated with a higher risk of mortality in patients with acute lung injury. The most consistent clinical risk factors for higher mortality have been sepsis as the cause of lung injury, chronic liver disease, underlying malignancy, older age, and higher severity of illness assessed by elevated acute physiology an...
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ژورنال
عنوان ژورنال: Journal of Critical Care
سال: 2012
ISSN: 0883-9441
DOI: 10.1016/j.jcrc.2011.06.015